University of Connecticut

Events Calendar

CCAM Seminar Series - Deymier

Thursday, April 12, 2018
12:00pm – 1:00pm

UConn Health
CGSB, CCAM Conference Room, R1673, 400 Farmington Ave

CCAM Seminar Series Speaker - Alix Deymier, assistant Professor, Derpartment of Biomedical Engineering, UConn Health Title: "Small Structures Big Effects: Multiscale Structure-Function Relationships in Musculoskeletal Tissues"

Abstract: Musculoskeletal injuries result in 65 million health care visits per year in the United States. The most common injuries are bone fractures and tendon tears or strains. In healthy musculoskeletal tissues, the body is able to decrease failure risks via complex hierarchical structures. These structures include composition gradients, energy absorbing and stress minimizing architectures, as well as multiphase composites. Disease, previous injury, and environmental factors, such as increased body acidity or muscle unloading, can modify the unique tissue structure and significantly increase failure risk and extent. To develop techniques for preventative and post-injury care it is therefore important to identify the musculoskeletal structures at multiple hierarchies and determine their mechanical roles. In addition, understanding these natural tissues can aid in the creation of new implants and devices. Alix Deymier has been investigating the role of architecture and composition from the nano- to the macro-scale on the mechanics of the musculoskeletal system via a variety of techniques including electron-energy loss spectroscopy, synchrotron x-ray diffraction, micromechanical testing, and microcomputed-tomography. She will present her work explaining how bones and tendons employ a hierarchy of structures and mechanisms to minimize failure and how these can be controlled and modified.


Tiffany x6103

Center for Cell Analysis and Modeling (primary)

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