University of Connecticut

Events Calendar

Neuroscience Faculty Seminar - Hu

Wednesday, January 17, 2018
10:00am – 11:00am

UConn Health
Low Learning Center

“BACE1 deletion reversing pre-formed amyloid deposition in the AD mouse model”

Presenter: Xiangyou Hu, PhD Research Assistant Professor Department of Neurosciences Cleveland Clinic Lerner Research Institute, Cleveland, OH

Citation(s): Hu X, Hu J, Lu D, Trapp BD, Yan R. Axonal and Schwann cell BACE1 is equally required for remyelination of peripheral nerves. J Neurosci 2015, 35:3806-14. https://www.ncbi.nlm.nih.gov/pubmed/?term=Axonal+and+Schwann+cell+BACE1+is+equally+required+for+remyelination+of+peripheral+nerves

Hu X, He W, Luo X, Tsubota K, Yan R. BACE1 Regulates Hippocampal Astrogenesis via the Jagged1-Notch Pathway. Cell Reports 2013, 4:40-49. https://www.ncbi.nlm.nih.gov/pubmed/?term=BACE1+Regulates+Hippocampal+Astrogenesis+via+the+Jagged1-Notch+Pathway

Hu X, Zhou X, He W, Yang J, Xiong W, Wong P, Wilson CG, Yan R. BACE1 deficiency causes altered neuronal activity and neurodegeneration. J Neurosci 2010, 30:8819-8829. https://www.ncbi.nlm.nih.gov/pubmed/?term=BACE1+deficiency+causes+altered+neuronal+activity+and+neurodegeneration

Hu X, He W, Diaconu C, Tang X, Kidd GJ, Macklin WB, Trapp BD, Yan R. Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves. FASEB J 2008, 22:2970-2980. https://www.ncbi.nlm.nih.gov/pubmed/?term=Genetic+deletion+of+BACE1+in+mice+affects+remyelination+of+sciatic+nerves

Hu X, Hicks CW, He W, Wong P, Macklin WB, Trapp BD, Yan R. BACE1 modulates myelination in the central and peripheral nervous system. Nature Neurosci 2006, 9:1520-1525. https://www.ncbi.nlm.nih.gov/pubmed/?term=BACE1+modulates+myelination+in+the+central+and+peripheral+nervous+system

Contact:

Jody Gridley, gridley@uchc.edu, 860-679-8787

Neuroscience Department at UConn Health (primary)

Control Panel