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CBE Seminar - Biofunctional Nanostructures for Characterizat

Thursday, April 12, 2018
9:30am – 10:30am

Storrs Campus
UTEB 150

Biofunctional Nanostructures for Characterization and Control of Single Electron Transfer Reactions

Dr. Paul W. Bohn Arthur J. Schmitt Professor Department of Chemical and Biomolecular Engineering Department of Chemistry and Biochemistry University of Notre Dame

One limit in chemical reaction engineering is the control of single reaction events, a goal which can now be achieved with the aid of a special nanophotonic-nanoelectrochemical architecture - the electrochemical zero-mode waveguide (E-ZMW). These bimodal nanopore structures link single electron-transfer events to changes in light emission through fluorigenic redox reactions, such as the conversion of flavin mononucleotide, FMN, which contains an isoalloxazine chromophore that is fluorescent in the oxidized state, FMN, but not in the reduced state, FMNH2. The bimodal optical- electrochemical functionality of the E-ZMW enables a variety of non-classical reaction studies ultimately enabling the characterization and control of reaction dynamics involving single molecules or single nanoparticles.

Paul W. Bohn received the B.S. in Chemistry from the University of Notre Dame in 1977 and the Ph.D. in Chemistry from the University of Wisconsin- Madison in 1981. After two-years at Bell Laboratories, Murray Hill, NJ as a Member of Technical Staff in the Special Materials Group, he joined the faculty at the University of Illinois at Urbana-Champaign (UIUC). While at UIUC, he served as Centennial Professor in Chemical Sciences, Professor of Chemistry, Professor in the Beckman Institute, Research Professor in the Micro and Nanotechnology Laboratory, Adjunct Professor of Materials Science and Engineering, and as a member of the Materials Research Laboratory. He also served as Interim Director of the School of Chemical Sciences in 1993-94, and Head of the Chemistry Department in 1994-99. In 2001-02, he was Interim Vice Chancellor for Research, the senior research officer of the UIUC campus. In August 2006, he joined the faculty at the University of Notre Dame as the Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering and Professor of Chemistry and Biochemistry. He served as Editor for the Americas for the Royal Society of Chemistry journal, Analyst, 2007-09 and a full term as Chair of the Editorial Board for Analyst 2010-14. Prof. Bohn also serves as Project Director for the Advanced Diagnostics and Therapeutics Initiative, one of five inaugural Strategic Research Initiatives established at Notre Dame in 2008 and as co-Director of the Analytical Sciences & Engineering at Notre Dame faculty hiring initiative. He has served on numerous editorial and scientific boards and is currently co-Editor of Annual Review of Analytical Chemistry. Dr. Bohn’s research interests include: (a) molecular approaches to, and uses of, nanotechnology, (b) integrated nanofluidic and microfluidic chemical measurement strategies for personal monitoring, and (c) correlated chemical imaging, especially of micro


Chemical & Biomolecular Engineering (primary), UConn Master Calendar

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